Description

n-(2-Fluoroethyl)Aniline is a versatile fluorinated aromatic amine building block, essential for introducing the 2-fluoroethylamino pharmacophore into target molecules. Its value lies in enabling the synthesis of advanced compounds with modified biological activity, metabolic stability, and physicochemical properties. This intermediate is particularly needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, including potential CNS-active agents, kinase inhibitors, and radiopharmaceuticals.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides where the fluoroethyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer Modification: Incorporation into polymer chains to impart specific chemical resistance, surface properties, or functionality.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized fluorinated dyes with unique color fastness and spectral properties.
• Chemical Research & Development: A valuable tool for medicinal and synthetic chemists exploring structure-activity relationships (SAR) and novel fluorination strategies.

Basic Information

Product Name	n-(2-Fluoroethyl)Aniline
CAS No.	459-40-5
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	N-(2-Fluoroethyl)aniline; 2-Fluoro-N-phenylethylamine; 1-Fluoro-2-(phenylamino)ethane; N-Phenyl-2-fluoroethylamine; Aniline, N-(2-fluoroethyl)-; 2-Fluoroethylphenylamine; (2-Fluoroethyl)phenylamine; N-(β-Fluoroethyl)aniline
EINECS	Contact for details

Quality Control

Our n-(2-Fluoroethyl)Aniline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.