Description

(4-Fluorophenyl)Acetone is a versatile fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in the strategic introduction of the fluorine atom and the reactive carbonyl group, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorophenyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom improves lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic and ketone functionality.
• Fine Chemical Production: A critical intermediate for manufacturing dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	(4-Fluorophenyl)Acetone
CAS No.	459-03-0
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(4-Fluorophenyl)-2-propanone; 4-Fluorophenylacetone; p-Fluorophenylacetone; 4'-Fluoroacetophenone; 4-Fluorobenzyl methyl ketone; 4-Fluoro-ω-methylacetophenone; USFDA UNII: 1B6H9U3Q4F
EINECS	Contact for details

Quality Control

Our (4-Fluorophenyl)Acetone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles and relevant ICH guidelines ensures material integrity for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.