Description

Acetamide, 2,2,2-Trifluoro-n-(2-Phenylethyl)- is a specialized fluorinated amide derivative, identified by CAS No. 458-85-5, valued for its unique trifluoromethyl group and aromatic side chain. This compound serves as a versatile and high-value building block in advanced organic synthesis, enabling the introduction of fluorine atoms to modulate the properties of target molecules. It is primarily sought by pharmaceutical and agrochemical research and development teams for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating the trifluoroacetamide pharmacophore.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine moiety improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Employed in the synthesis of specialty polymers with tailored thermal, chemical, and surface properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for amidation and fluorination reactions in complex molecule construction.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new synthetic methodologies and material science.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Phenylethyl)-
CAS No.	458-85-5
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	N-(2-Phenylethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-phenylethyl)acetamide; α,α,α-Trifluoro-N-(2-phenylethyl)acetamide; 2-Phenylethyltrifluoroacetamide; Trifluoroacetic acid 2-phenylethylamide; TFA-PEA; N-Phenethyltrifluoroacetamide
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.