Description

3-Fluoro-4-Iodoanisole is a high-purity halogenated anisole derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and iodine atoms on the aromatic ring, which enables selective functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated aromatic systems.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of advanced electronic materials for displays and lighting due to its stable aromatic core and halogen substituents.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Fluorine Chemistry Studies: Utilized in research to study the effects of fluorine substitution on the reactivity and physical properties of aromatic compounds.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated aromatic intermediates.

Basic Information

Product Name	3-Fluoro-4-Iodoanisole
CAS No.	458-51-5
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	1-Fluoro-2-Iodo-4-Methoxybenzene; 4-Iodo-3-Fluoroanisole; 3-Fluoro-4-Iodomethoxybenzene; 2-Fluoro-1-Iodo-4-Methoxybenzene; 1-Methoxy-2-fluoro-4-iodobenzene; 4-Methoxy-2-fluoro-1-iodobenzene; Anisole, 3-fluoro-4-iodo-; 3-Fluoro-p-iodoanisole
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodoanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.