Description

4-Bromo-3-Fluoroanisole is a halogenated aromatic ether building block of significant importance in advanced organic synthesis. Its value lies in its dual functionality, where the bromine and fluorine substituents serve as orthogonal handles for selective cross-coupling and nucleophilic substitution reactions. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Key synthetic intermediate in the preparation of pharmaceutical candidates, especially those targeting central nervous system (CNS) disorders.
• Building block for the synthesis of advanced agrochemicals, including herbicides and fungicides.
• Precursor in material science for creating functionalized monomers used in specialty polymers.
• Versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Starting material for the development of liquid crystals and organic electronic materials.
• Intermediate in fine chemical synthesis for flavors, fragrances, and dyes.

Basic Information

Product Name	4-Bromo-3-Fluoroanisole
CAS No.	458-50-4
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	1-Bromo-2-fluoro-4-methoxybenzene; 3-Fluoro-4-bromoanisole; 4-Bromo-3-fluorophenyl methyl ether; 2-Fluoro-4-methoxybromobenzene; Benzene, 1-bromo-2-fluoro-4-methoxy-; 4-Methoxy-2-fluorobromobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoroanisole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP standards where applicable, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.