Description

3',4'-Difluoroacetanilide is a high-purity fluorinated aniline derivative, serving as a critical pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate difluorophenyl motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with improved efficacy and selectivity.
• Liquid Crystal Materials: Used in the research and production of fluorinated components for liquid crystal displays (LCDs).
• Organic Synthesis & Research: A valuable reagent for introducing the difluorophenyl group in complex organic transformations and medicinal chemistry research.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing specialized fluorinated dyes and functional pigments.

Basic Information

Product Name	3',4'-Difluoroacetanilide
CAS No.	458-11-7
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	N-(3,4-Difluorophenyl)acetamide; 1-(3,4-Difluorophenyl)acetamide; 3,4-Difluoroacetanilide; Acetamide, N-(3,4-difluorophenyl)-; 3,4-DFA; NSC 406925; AI3-52095; CCRIS 9356
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoroacetanilide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.