Description

Acetamide, 2,2,2-Trifluoro-n-(4-Ethoxyphenyl)- is a specialized fluorinated acetamide derivative, recognized for its unique trifluoromethyl and ethoxyphenyl functional groups. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is essential for researchers and manufacturers in fine chemical, pharmaceutical, and agrochemical industries seeking to incorporate fluorine-containing motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the fluorinated moiety enhances biological activity and stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials due to its specific electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, amidation processes, and as a scaffold for constructing complex heterocyclic compounds.
• Chemical Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(4-Ethoxyphenyl)-
CAS No.	457-53-4
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	N-(4-Ethoxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(4-ethoxyphenyl)acetamide; 4'-Ethoxy-2,2,2-trifluoroacetanilide; p-Ethoxy-α,α,α-trifluoroacetanilide; α,α,α-Trifluoro-p-ethoxyacetanilide; TFEA; Trifluoroacet-p-phenetidide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(4-Ethoxyphenyl)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a fine chemical intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.