Description

Benzenepropanoic Acid, α-Fluoro- is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom improves lipophilicity and target binding.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers and liquid crystals with unique optical or electronic properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships (SAR).
• Peptidomimetics & Bioisosteres: The α-fluoro carboxylic acid moiety is used to create hydrolytically stable analogs of natural peptides and amino acids.

Basic Information

Product Name	Benzenepropanoic Acid, α-Fluoro-
CAS No.	457-45-4
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	3-Fluoro-3-phenylpropanoic acid; α-Fluorohydrocinnamic acid; (RS)-3-Fluoro-3-phenylpropionic acid; (±)-3-Fluoro-3-phenylpropanoic acid; 3-Fluoro-3-phenylpropionic acid; DL-3-Fluoro-3-phenylpropanoic acid; Fluorohydrocinnamic acid; Benzenepropanoic acid, 3-fluoro-
EINECS	Contact for details

Quality Control

Our production of Benzenepropanoic Acid, α-Fluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets precise customer specifications. We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.