Description

Trifluoromethylthiobenzene is a high-value organosulfur and organofluorine building block essential for advanced chemical synthesis. Its unique combination of a strong electron-withdrawing trifluoromethylthio group and an aromatic ring makes it a critical intermediate for developing novel compounds with enhanced properties. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the SCF₃ group can improve biological activity and environmental profile.
• Material Science: Serves as a monomer or modifier in the development of specialty polymers and advanced materials with specific surface or electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Research: A valuable reagent for introducing the pharmacologically privileged trifluoromethylthio moiety into complex molecular architectures.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and functional pigments.

Basic Information

Item	Detail
Product Name	Trifluoromethylthiobenzene
CAS No.	456-56-4
Molecular Formula	C₇H₅F₃S
Molecular Weight	178.18 g/mol
Synonyms	(Trifluoromethylthio)benzene; Phenyl trifluoromethyl sulfide; α,α,α-Trifluorothioanisole; Benzene, (trifluoromethylthio)-; S-(Trifluoromethyl)thiophenol; Thiobenzotrifluoride; SC-762
EINECS	Contact for details

Quality Control

Our Trifluoromethylthiobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our global customers with the necessary documentation for their regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.