Description

3-(Trifluoromethyl)Anisole is a versatile fluorinated aromatic building block characterized by its trifluoromethyl and methoxy substituents. This compound is valued for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds requiring trifluoromethylated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Organic Synthesis & Catalysis: Employed as a reagent or ligand in cross-coupling reactions and other catalytic processes in fine chemical manufacturing.
• Fluorine Chemistry Research: A valuable standard and starting material for academic and industrial research into new fluorination methodologies.

Basic Information

Product Name	3-(Trifluoromethyl)Anisole
CAS No.	454-90-0
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	m-(Trifluoromethyl)anisole; 1-Methoxy-3-(trifluoromethyl)benzene; 3-Methoxybenzotrifluoride; 3-Trifluoromethylphenyl methyl ether; α,α,α-Trifluoro-m-cresol methyl ether; m-Trifluoromethylanisole; 3-(Trifluoromethoxy)benzene (incorrect but common search term)
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Anisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.