Description

2-Fluoro-5-Nitroanisole is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines an electron-withdrawing nitro group and a fluorine atom on an anisole scaffold, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Key synthetic intermediate in the development of novel pharmaceutical compounds, particularly for targeted therapies.
• Building block for the synthesis of advanced agrochemicals, including herbicides and fungicides.
• Precursor in the research and production of liquid crystal materials and other specialty electronic chemicals.
• Used in organic light-emitting diode (OLED) material research as a functionalized aromatic component.
• Intermediate for the preparation of dyes and pigments with specific light-fastness properties.
• Starting material in academic and industrial R&D for exploring new fluorination reactions and coupling methodologies.

Basic Information

Product Name	2-Fluoro-5-Nitroanisole
CAS No.	454-16-0
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	1-Fluoro-2-Methoxy-4-Nitrobenzene; 2-Methoxy-1-Fluoro-4-Nitrobenzene; 5-Nitro-2-Fluoroanisole; Anisole, 2-fluoro-5-nitro-; Benzene, 1-fluoro-2-methoxy-4-nitro-; 4-Nitro-2-fluoroanisole
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitroanisole is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.