Description

N,n-Diethyl-3-Oxo-4,4,4-Trifluorobutyramide is a versatile fluorinated organic compound that serves as a key intermediate in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl and keto-amide functional groups, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and coatings with tailored surface properties and chemical resistance.
• Organic Synthesis & Research: A valuable reagent for constructing complex molecules in academic and industrial R&D laboratories, especially for introducing fluorinated segments.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated components for display materials and electronic-grade chemicals.

Basic Information

Product Name	N,n-Diethyl-3-Oxo-4,4,4-Trifluorobutyramide
CAS No.	452-13-1
Molecular Formula	C8H12F3NO2
Molecular Weight	211.18 g/mol
Synonyms	4,4,4-Trifluoro-3-oxo-N,N-diethylbutyramide; 3-Oxo-4,4,4-trifluoro-N,N-diethylbutyramide; N,N-Diethyl-4,4,4-trifluoroacetoacetamide; Diethyl trifluoroacetoacetamide; 1,1,1-Trifluoro-4-(diethylamino)-2,4-butanedione; Ethyl Trifluoroacetoacetate Diethylamide; TFAA Diethylamide; CAS 452-13-1
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-3-Oxo-4,4,4-Trifluorobutyramide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.