Description

2,4-Difluoroanisole is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate for introducing fluorine atoms and methoxy groups into complex molecular architectures, enabling the development of novel materials and active ingredients. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A versatile synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the manufacture of modern, high-performance herbicides and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved display performance.
• Polymer & Resin Modifier: Employed to introduce fluorine into polymer chains, enhancing properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Building Block: Facilitates various cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions in complex molecule construction.
• Dye & Pigment Intermediate: Used in the production of specialized fluorinated dyes and pigments for high-value applications.

Basic Information

Product Name	2,4-Difluoroanisole
CAS No.	452-10-8
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	1,3-Difluoro-4-methoxybenzene; 2,4-Difluorophenyl methyl ether; 4-Methoxy-1,3-difluorobenzene; Anisole, 2,4-difluoro-; Benzene, 1,3-difluoro-4-methoxy-; 2,4-DFA; 2,4-Difluoromethoxybenzene
EINECS	Contact for details

Quality Control

Our 2,4-Difluoroanisole is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical properties are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Density (20°C)	~1.22 g/cm³
Refractive Index (n20D)	~1.465

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.