Description

2-Bromo-4-Fluoroanisole is a versatile halogenated anisole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, where the bromine and fluorine substituents on the aromatic ring enable selective functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with fluorinated or brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive bromo and fluoro groups.
• Chemical Research & Development: Essential for academic and industrial R&D in exploring new synthetic pathways and novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogen atoms modify color properties and stability.

Basic Information

Item	Detail
Product Name	2-Bromo-4-Fluoroanisole
CAS No.	452-08-4
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	1-Bromo-2-fluoro-4-methoxybenzene; 4-Fluoro-2-bromoanisole; 2-Bromo-4-fluoro-1-methoxybenzene; 2-Bromo-4-fluorophenyl methyl ether; 2-Bromo-4-fluoroanisole; Benzene, 1-bromo-2-fluoro-4-methoxy-; 452-08-4; 2-Bromo-4-fluoromethoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.