Description

1,3-Dichloro-4-(Trifluoromethoxy)Benzene is a high-value halogenated aromatic building block characterized by its unique trifluoromethoxy substituent. This compound is essential for advanced chemical synthesis, offering a versatile scaffold for introducing specific steric and electronic properties into target molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or modifier in the production of high-performance polymers with specific thermal and chemical resistance properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to construct complex molecular architectures.

Basic Information

Product Name	1,3-Dichloro-4-(Trifluoromethoxy)Benzene
CAS No.	451-85-4
Molecular Formula	C7H3Cl2F3O
Molecular Weight	231.00 g/mol
Synonyms	4-(Trifluoromethoxy)-1,3-dichlorobenzene; 1,3-Dichloro-4-(trifluoromethoxy)benzene; 2,4-Dichloro-1-(trifluoromethoxy)benzene; Benzene, 1,3-dichloro-4-(trifluoromethoxy)-; NSC 403119; 1,3-Dichloro-α,α,α-trifluoro-p-cresol methyl ether
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.