Description

2-(4-Fluorobenzoyl)Aminopropionic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals. The product is supplied with rigorous quality control to ensure batch-to-batch consistency and reliability for critical applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the fluorine moiety for enhanced bioactivity and environmental stability.
• Peptidomimetics & Bioactive Molecules: Serves as a constrained amino acid derivative for creating peptide analogs and other bioactive compounds with improved metabolic stability.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where fluorinated aromatic groups impart unique physical properties.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic & R&D: A valuable reagent for medicinal chemistry and organic synthesis research in academic and industrial settings.

Basic Information

Product Name	2-(4-Fluorobenzoyl)Aminopropionic Acid
CAS No.	451-28-5
Molecular Formula	C10H10FNO3
Molecular Weight	211.19 g/mol
Synonyms	N-(4-Fluorobenzoyl)-DL-alanine; DL-2-[(4-Fluorobenzoyl)amino]propanoic Acid; 2-[(4-Fluorobenzoyl)amino]propionic Acid; 4-Fluoro-N-(1-carboxyethyl)benzamide; Alanine, N-(p-fluorobenzoyl)-; Fmoc-Ala(4-F-Bz)-OH (protected form precursor); p-Fluorobenzoylamino-propionic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzoyl)Aminopropionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.