Description

4-Fluoro-1-Iodo-2-Methoxybenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and methoxy substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aryl iodide moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the bioactivity-modifying properties of fluorine.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the reactive iodine atom.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.
• Ligand and Catalyst Preparation: Used to synthesize complex ligands for catalysis or as part of catalyst frameworks themselves.

Basic Information

Product Name	4-Fluoro-1-Iodo-2-Methoxybenzene
CAS No.	450-90-8
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	1-Fluoro-4-iodo-2-methoxybenzene; 2-Methoxy-4-fluoroiodobenzene; 4-Fluoro-2-methoxy-1-iodobenzene; 4-Fluoro-2-methoxyiodobenzene; 2-Methoxy-4-fluoro-1-iodobenzene; 4-Fluoro-o-iodoanisole; 4-Fluoro-2-iodoanisole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Iodo-2-Methoxybenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.