Description

2-Bromo-5-Fluoroanisole is a versatile halogenated anisole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the aromatic ring, makes it a valuable intermediate for introducing specific reactivity and electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro groups can enhance target binding and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic and optoelectronic materials, contributing to desired molecular alignment and electronic properties.
• Cross-Coupling Reactions: Acts as a competent substrate in palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig aminations, enabling the construction of complex biaryl and heteroaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new synthetic methodologies and constructing molecular libraries for screening.
• Functional Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where halogen atoms fine-tune color properties and lightfastness.

Basic Information

Product Name	2-Bromo-5-Fluoroanisole
CAS No.	450-88-4
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	1-Bromo-4-fluoro-2-methoxybenzene; 4-Fluoro-2-methoxybromobenzene; 2-Bromo-4-fluoroanisole; 5-Fluoro-2-bromoanisole; Benzene, 1-bromo-4-fluoro-2-methoxy-; Anisole, 2-bromo-5-fluoro-; 2-Methoxy-4-fluorobromobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.