Description

2-(3-Fluorophenyl)-3-Oxobutanenitrile is a versatile fluorinated organic building block characterized by its ketone and nitrile functional groups. This compound is critical for the synthesis of complex molecules, offering a reactive handle for further chemical modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and as a building block in complex organic synthesis, including cyclization and condensation reactions.
• Ligand and Catalyst Preparation: Useful for synthesizing novel chelating ligands or organocatalysts due to its reactive carbonyl and nitrile groups.

Basic Information

Product Name	2-(3-Fluorophenyl)-3-Oxobutanenitrile
CAS No.	446-74-2
Molecular Formula	C10H8FNO
Molecular Weight	177.17 g/mol
Synonyms	3'-Fluoro-2-oxobutyronitrile; 3-Oxo-2-(3-fluorophenyl)butanenitrile; 2-(3-Fluorophenyl)acetoacetonitrile; 3-Fluorophenyl methyl ketone cyanide; 1-(3-Fluorophenyl)-2-cyano-1-propanone; 3-Fluoro-α-acetylbenzyl cyanide; Butanenitrile, 2-(3-fluorophenyl)-3-oxo-
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-3-Oxobutanenitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.