Description

Benzene, 2-Chloro-1-Fluoro-3-Methoxy- is a halogenated and methoxylated benzene derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its structure contributes to biological activity.
• Liquid Crystal Materials: Serves as a fundamental building block for creating liquid crystal molecules used in display technologies (LCDs).
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Fine Chemical Synthesis: A versatile intermediate for synthesizing complex dyes, pigments, and other specialty organic compounds.
• Research & Development: Used in academic and industrial R&D labs for method development and exploring new chemical reactions.

Basic Information

Product Name	Benzene, 2-Chloro-1-Fluoro-3-Methoxy-
CAS No.	446-60-6
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	1-Chloro-2-fluoro-3-methoxybenzene; 2-Chloro-1-fluoro-3-methoxybenzene; 3-Methoxy-2-chloro-1-fluorobenzene; 2-Chloro-3-methoxyfluorobenzene; 1-Fluoro-2-chloro-3-methoxybenzene; o-Chloro-m-fluoroanisole; 446-60-6 (CAS)
EINECS	Contact for details

Quality Control

Our Benzene, 2-Chloro-1-Fluoro-3-Methoxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including GC/HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with every shipment, documenting compliance with agreed specifications. Our quality system supports cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.30 g/cm³
Boiling Point	~195-200°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.