Description

2-Bromo-3-Fluoroanisole is a halogenated anisole derivative, a versatile and high-purity aromatic building block essential for advanced organic synthesis. Its core value lies in its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and the synthesis of liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its electron-withdrawing halogen groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	2-Bromo-3-Fluoroanisole
CAS No.	446-59-3
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	1-Bromo-2-fluoro-3-methoxybenzene; 3-Bromo-2-fluoroanisole; 2-Fluoro-3-bromoanisole; 2-Fluoro-3-methoxybromobenzene; 3-Methoxy-2-fluorobromobenzene; Benzene, 1-bromo-2-fluoro-3-methoxy-; (2-Bromo-3-fluorophenyl) methyl ether
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.