Description

3,4-Methylenedioxyphenylacetonitrile CAS NO 443-92-5 is a versatile and high-value organic nitrile compound characterized by its methylenedioxy-substituted aromatic ring. This structure makes it a critical advanced pharmaceutical intermediate and a key building block in fine chemical synthesis. It is primarily sought after by research institutions, pharmaceutical manufacturers, and agrochemical companies for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex heterocyclic structures.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a starting material for dyes, pigments, and other specialty organic compounds.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	3,4-Methylenedioxyphenylacetonitrile
CAS No.	443-92-5
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	1,3-Benzodioxole-5-acetonitrile; Piperonylacetonitrile; 3,4-(Methylenedioxy)benzyl cyanide; 5-Cyanomethyl-1,3-benzodioxole; MDBN; Heliotropylacetonitrile
EINECS	207-150-8

Quality Control

Our 3,4-Methylenedioxyphenylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.