Description

2,6-Dibromo-4-Fluoroanisole is a halogenated anisole derivative, a versatile and high-value fluorinated aromatic building block. Its unique structure, featuring bromine and fluorine substituents, makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing active ingredients, liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or as a precursor for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance metabolic stability and binding affinity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies (LCDs) due to its ability to influence molecular polarity and mesophase stability.
• Organic Synthesis & Catalysis Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) as a substrate to create complex biaryl structures for catalytic and material science applications.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, including high-performance resins and fluorinated materials with unique thermal and chemical resistance.
• Chemical Reference Standard: Used in analytical laboratories as a standard for method development, calibration, and quality control in chromatographic analysis.

Basic Information

Item	Details
Product Name	2,6-Dibromo-4-Fluoroanisole
CAS No.	443-41-4
Molecular Formula	C7H5Br2FO
Molecular Weight	283.92 g/mol
Synonyms	4-Fluoro-2,6-dibromoanisole; 1,3-Dibromo-5-fluoro-2-methoxybenzene; 2,6-Dibromo-4-fluoro-1-methoxybenzene; 2-Methoxy-1,3-dibromo-5-fluorobenzene; Anisole, 2,6-dibromo-4-fluoro-; 2,6-Dibromo-4-fluoromethoxybenzene
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-4-Fluoroanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific grade requirements (e.g., research grade, >98% purity), our technical team is available to discuss tailored quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.