Description

1,4-Bis(Trifluoromethyl)-Benzene is a high-purity fluorinated aromatic compound, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups in the para position, makes it an invaluable intermediate for creating materials with enhanced thermal stability and chemical resistance. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty polymer industries, where precise fluorination is required to modify compound properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl groups contribute to efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fundamental component in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing electronic properties and device performance.
• Specialty Polymer Monomer: Employed in the production of high-performance polymers, such as polyimides and polyarylates, imparting superior thermal stability, low dielectric constant, and chemical resistance.
• Catalyst Ligand Precursor: Acts as a precursor for synthesizing sophisticated ligands used in catalysis, enabling more efficient and selective chemical transformations.
• Organic Synthesis & R&D: A versatile reagent in academic and industrial research laboratories for exploring novel fluorinated compounds and reaction pathways.

Basic Information

Product Name	1,4-Bis(Trifluoromethyl)-Benzene
CAS No.	433-19-2
Molecular Formula	C8H4F6
Molecular Weight	214.11 g/mol
Synonyms	p-Bis(trifluoromethyl)benzene; 1,4-Di(trifluoromethyl)benzene; α,α,α,α',α',α'-Hexafluoro-p-xylene; p-Xylene, α,α,α,α',α',α'-hexafluoro-; Benzene, 1,4-bis(trifluoromethyl)-; Hexafluoro-p-xylene; p-(Trifluoromethyl)benzotrifluoride
EINECS	207-087-5

Quality Control

Our 1,4-Bis(Trifluoromethyl)-Benzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.50 - 1.55 g/mL
Refractive Index (n20D)	1.380 - 1.390

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.