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Phosphinous Amide, N,n-Dimethyl-P,p-Bis(Trifluoromethyl)- CAS NO 432-01-9


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CAS No.:432-01-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Phosphinous Amide, N,n-Dimethyl-P,p-Bis(Trifluoromethyl)- is a specialized organophosphorus compound featuring a unique phosphinous amide core flanked by trifluoromethyl groups. This structure makes it a valuable intermediate for synthesizing advanced materials and ligands in catalysis, particularly where electron-withdrawing properties and steric bulk are required. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
  • Catalyst Ligand Precursor: Serves as a precursor for sophisticated phosphine-based ligands used in cross-coupling reactions and asymmetric catalysis.
  • Agrochemical Synthesis: Intermediate in the production of advanced, fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
  • Material Science Research: Used in the development of fluorinated polymers, coatings, and electronic materials with specific thermal and chemical resistance properties.
  • Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex molecules containing P-N and C-F bonds.

Basic Information

Product Name Phosphinous Amide, N,n-Dimethyl-P,p-Bis(Trifluoromethyl)-
CAS No. 432-01-9
Molecular Formula C6H6F6NP
Molecular Weight 261.08 g/mol
Synonyms N,N-Dimethyl-P,P-bis(trifluoromethyl)phosphinous amide; Bis(trifluoromethyl)phosphinous acid dimethylamide; Phosphonous diamide, N,N-dimethyl-P,P-bis(trifluoromethyl)-; (Dimethylamino)bis(trifluoromethyl)phosphine; DTMPA
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Quality Control

Our production of Phosphinous Amide, N,n-Dimethyl-P,p-Bis(Trifluoromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and fluorides. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0%
1H NMR Conforms
19F NMR Conforms
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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