Description

1,1,1-Tribromotrifluoroacetone is a specialized halogenated ketone building block, valued for its unique trifluoromethyl and tribromomethyl functional groups. This compound serves as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering a versatile handle for introducing fluorine and bromine atoms. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated or brominated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the halogenated structure can contribute to improved efficacy and environmental profile.
• Fluorinated Material Production: Serves as a building block for creating specialty polymers, liquid crystals, and other advanced materials that benefit from fluorine's unique properties.
• Chemical Research & Development: Employed in organic synthesis as a versatile reagent for introducing multiple halogen atoms in a single step, facilitating structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands and catalysts for transition metal-mediated reactions.

Basic Information

Product Name	1,1,1-Tribromotrifluoroacetone
CAS No.	431-91-4
Molecular Formula	C3Br3F3O
Molecular Weight	344.74 g/mol
Synonyms	Trifluoroacetyl Tribromomethane; Tribromotrifluoroacetone; 1,1,1-Tribromo-3,3,3-trifluoroacetone; 3,3,3-Trifluoro-1,1,1-tribromoacetone; Tribromotrifluoro-2-propanone; Acetone, 1,1,1-tribromo-3,3,3-trifluoro-; Perfluorotribromoacetone; 2-Propanone, 1,1,1-tribromo-3,3,3-trifluoro-
EINECS	207-094-5

Quality Control

Our 1,1,1-Tribromotrifluoroacetone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.