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2-Chloro-1,1,1,3,3,3-Hexafluoropropane CAS NO 431-87-8


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CAS No.:431-87-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-1,1,1,3,3,3-Hexafluoropropane is a halogenated hydrocarbon with a unique combination of chlorine and fluorine atoms, making it a valuable specialty chemical intermediate. Its primary value lies in its role as a key building block for synthesizing advanced fluorinated compounds used in high-performance materials and pharmaceuticals. This product is essential for R&D chemists and process engineers in the agrochemical, pharmaceutical, and advanced polymer industries seeking to introduce specific fluorinated functionalities into their target molecules.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the introduction of fluorine atoms can significantly improve efficacy and environmental profile.
  • Fluorinated Polymer & Material Science: Acts as a monomer or modifier in the development of specialty polymers, coatings, and elastomers with superior chemical resistance, thermal stability, and low surface energy.
  • Refrigerant & Propellant Formulation: Employed in the research and development of next-generation, low-global-warming-potential (GWP) refrigerants, blowing agents, and aerosol propellants.
  • Electronics & Semiconductor Industry: Utilized in plasma etching processes and as a precursor for depositing fluorinated thin films essential in microelectronics fabrication.
  • Organic Synthesis & Catalysis: A versatile reagent in fluorination reactions and cross-coupling chemistry for constructing complex organic molecules in academic and industrial research settings.

Basic Information

Product Name 2-Chloro-1,1,1,3,3,3-Hexafluoropropane
CAS No. 431-87-8
Molecular Formula C3HClF6
Molecular Weight 186.47 g/mol
Synonyms 1,1,1,3,3,3-Hexafluoro-2-chloropropane; 2-Chlorohexafluoropropane; HCFC-216ca; Freon 216ca; Propane, 2-chloro-1,1,1,3,3,3-hexafluoro-; R-216ca; 431-87-8
EINECS 207-080-8

Quality Control

Every batch of 2-Chloro-1,1,1,3,3,3-Hexafluoropropane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of your synthesis and process. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by GC, GC-MS, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources, open flames, and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-25°C.

Specification

Item Specification
Appearance Colorless clear liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.1%
Non-volatile Residue ≤ 0.01%
Acidity (as HCl) ≤ 0.001%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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