Description

Pentafluoroacetone is a highly reactive fluorinated ketone and a versatile building block in advanced organic synthesis. Its unique structure, featuring five fluorine atoms, makes it a critical intermediate for introducing trifluoromethyl and other fluorinated groups into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced metabolic stability, lipophilicity, and biological activity. Pentafluoroacetone CAS NO 431-71-0 is supplied as a high-purity gaseous material to meet the stringent demands of modern fluorination chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of trifluoromethyl-containing active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used to manufacture advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Reagent: A fundamental reagent for introducing the -COCF3 moiety and for use in cycloaddition and nucleophilic addition reactions in fine chemical production.
• Electronics & Semiconductor Industry: Potential use in the deposition of fluorine-doped thin films and as a precursor in chemical vapor deposition (CVD) processes.
• Research & Development: Indispensable for academic and industrial R&D focused on fluorine chemistry and the development of new fluorinated compounds.

Basic Information

Product Name	Pentafluoroacetone
CAS No.	431-71-0
Molecular Formula	C3F5HO
Molecular Weight	164.03 g/mol
Synonyms	Perfluoroacetone; 1,1,1,3,3-Pentafluoro-2-propanone; 1,1,1,3,3-Pentafluoroacetone; Acetone, pentafluoro-; Pentafluoro-2-propanone; Trifluoroacetyl fluoride; Perfluoro-2-propanone; CF3COCF3
EINECS	207-079-2

Quality Control

Our Pentafluoroacetone is produced and handled under strict quality management protocols. Each batch is analyzed to ensure it meets high-purity standards suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with detailed specifications including assay, identity confirmation, and impurity profiles. Our quality systems are designed to ensure batch-to-batch consistency and reliable supply for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and gaseous nature, this product must be stored in a certified pressure-rated cylinder or vessel in a cool, well-ventilated area, away from heat sources and incompatible materials. Store under an inert atmosphere if required for specific purity grades. Keep container tightly sealed when not in use to prevent loss and contamination.

Specification

Item	Specification
Appearance	Colorless Gas
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Purity (GC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Acidity (as HF)	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.