Description

2,2,2-Trifluoro-n-Methylacetimidamide is a specialized fluorinated acetimidamide derivative, a key building block in advanced organic synthesis. Its trifluoromethyl group imparts unique electronic and steric properties, making it a valuable intermediate for creating compounds with enhanced metabolic stability and lipophilicity. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used to incorporate the trifluoromethyl group into novel herbicides, fungicides, and insecticides to improve their efficacy and environmental profile.
• Material Science Research: Serves as a building block for developing advanced fluorinated polymers and liquid crystals with specific thermal and chemical resistance properties.
• Organic Synthesis Reagent: Employed in nucleophilic addition and cyclization reactions to introduce the -C(CF3)=N- moiety into complex molecular architectures.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the reactivity and applications of fluorinated imidamides.

Basic Information

Product Name	2,2,2-Trifluoro-n-Methylacetimidamide
CAS No.	431-41-4
Molecular Formula	C3H5F3N2
Molecular Weight	126.08 g/mol
Synonyms	N-Methyl-2,2,2-trifluoroacetimidamide; 2,2,2-Trifluoro-N-methylacetimidamide; Trifluoroacetamidine, N-methyl-; N-Methyltrifluoroacetamidine; 1-Methyl-2,2,2-trifluoroethanimidamide; TFAA-N-Me; Methyltrifluoroacetimidamide; CAS 431-41-4
EINECS	207-087-2

Quality Control

Our 2,2,2-Trifluoro-n-Methylacetimidamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.