Description

3-Amino-1,1,1-trifluoro-2-propanol is a versatile fluorinated amino alcohol building block of significant industrial importance. Its unique structure, combining a trifluoromethyl group with both amino and hydroxyl functionalities, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce fluorine motifs to enhance molecular properties such as metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Complex Ligand Synthesis: Useful in preparing chiral ligands and catalysts for asymmetric synthesis in fine chemical production.
• Research & Development: A valuable reagent for medicinal chemistry and material science research exploring fluorine chemistry.

Basic Information

Product Name	3-Amino-1,1,1-trifluoro-2-propanol
CAS No.	431-38-9
Molecular Formula	C3H6F3NO
Molecular Weight	129.08 g/mol
Synonyms	1,1,1-Trifluoro-3-amino-2-propanol; 3-Amino-1,1,1-trifluoroisopropanol; 3-Amino-2-hydroxy-1,1,1-trifluoropropane; 2-Propanol, 3-amino-1,1,1-trifluoro-; 3-Aminotrifluoroisopropanol; 1,1,1-Trifluoro-3-aminopropan-2-ol; α-(Trifluoromethyl)-β-aminoethanol; TFAP
EINECS	207-080-9

Quality Control

Our 3-Amino-1,1,1-trifluoro-2-propanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.