Description

2,3,3,3-Tetrafluoropropionitrile is a versatile fluorinated nitrile building block with unique chemical reactivity. Its molecular structure makes it a critical intermediate for synthesizing advanced fluorinated compounds used in high-performance materials and pharmaceuticals. This product is essential for R&D and production chemists in the agrochemical, pharmaceutical, and specialty polymer industries seeking to incorporate fluorine for enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) and agrochemicals, where fluorine atoms improve metabolic stability and bioavailability.
• Fluorinated Polymer Synthesis: Serves as a monomer or co-monomer for creating specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Electrolyte Additive for Lithium-Ion Batteries: Used in the formulation of advanced electrolytes to improve battery performance, cycle life, and safety at high voltages.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cyclization reactions to introduce the tetrafluoropropionitrile moiety into complex molecules.
• Refrigerant and Propellant Research: Investigated as a potential component in next-generation, low global warming potential (GWP) refrigerants and propellant blends.
• Surface Modification Agent: Used to impart oleophobic and hydrophobic characteristics to surfaces in advanced material coatings.

Basic Information

Product Name	2,3,3,3-Tetrafluoropropionitrile
CAS No.	431-32-3
Molecular Formula	C₃HF₄N
Molecular Weight	127.04 g/mol
Synonyms	2,3,3,3-Tetrafluoropropanenitrile; Perfluoropropionitrile; Tetrafluoropropiononitrile; HFO-1234yf nitrile; 1,1,2,2-Tetrafluoroethyl cyanide; R-1234yf nitrile; TFPN; 431-32-3
EINECS	207-079-5

Quality Control

Our 2,3,3,3-Tetrafluoropropionitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its highly volatile nature, keep containers tightly sealed and under appropriate pressure. Recommended storage temperature is 2-8°C to maximize stability. Handle and store under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (as HF)	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.