Description

1,1-Difluoropropan-2-Amine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoromethyl group adjacent to a primary amine, makes it a valuable precursor for introducing fluorine atoms into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, potentially enhancing metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Used in the synthesis of novel herbicides, insecticides, and fungicides where fluorine substitution is desired for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and coatings with tailored surface properties.
• Ligand Synthesis: Employed in the creation of novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A fundamental building block in academic and industrial laboratories exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	1,1-Difluoropropan-2-Amine
CAS No.	431-00-5
Molecular Formula	C3H7F2N
Molecular Weight	95.09 g/mol
Synonyms	2-Amino-1,1-difluoropropane; 1,1-Difluoro-2-aminopropane; 1,1-Difluoroisopropylamine; 2-Propanamine, 1,1-difluoro-; α,α-Difluoroisopropylamine
EINECS	207-069-8

Quality Control

Our 1,1-Difluoropropan-2-Amine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain purity and prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.