Description

2,2-Difluoropropane-1,3-Diol is a versatile fluorinated diol building block of significant interest in advanced chemical synthesis. Its unique structure, featuring two primary hydroxyl groups and two fluorine atoms on a central carbon, makes it a valuable precursor for introducing fluorine into target molecules, which can dramatically alter their physical and biological properties. This compound is particularly sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel compounds with enhanced stability, bioavailability, or surface activity.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where fluorine substitution is used to modulate metabolism, potency, and membrane permeability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for synthesizing fluorinated polyesters, polyurethanes, and epoxy resins, imparting desirable properties like chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials, where fluorine atoms contribute to low viscosity and high dielectric anisotropy.
• Surface Active Agents: Acts as a building block for fluorinated surfactants and coatings that provide exceptional oil and water repellency (e.g., for textiles, carpets, and paper).
• Organic Synthesis Building Block: A versatile reagent for nucleophilic substitution reactions and the preparation of complex fluorinated ethers, esters, and other fine chemicals.

Basic Information

Product Name	2,2-Difluoropropane-1,3-Diol
CAS No.	428-63-7
Molecular Formula	C3H6F2O2
Molecular Weight	112.08 g/mol
Synonyms	2,2-Difluoro-1,3-propanediol; 1,3-Propanediol, 2,2-difluoro-; Difluoropropanediol; 2,2-Difluorotrimethylene Glycol; DFPD; NSC 5188; 428-63-7; 2,2-Difluoropropane-1,3-diol
EINECS	207-055-9

Quality Control

Our 2,2-Difluoropropane-1,3-Diol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency for research and industrial use. Certificates of Analysis (COA) detailing specific results for identity, assay, and impurity profiles are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to prevent decomposition; consider storage under an inert atmosphere such as nitrogen for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.