Description

Triphenylmethyl Fluoride is a specialized organofluorine compound valued for its role as a versatile reagent and protecting group in advanced organic synthesis. Its unique structure, featuring a highly stable trityl group bonded to fluorine, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination and selective protection strategies are required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms or protecting sensitive functional groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and plant growth regulators that benefit from fluorinated components.
• Organic Synthesis Reagent: Serves as a fluorinating agent and a robust protecting group for alcohols and other nucleophiles in multi-step synthetic routes.
• Materials Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Useful as a tool compound for modifying peptides, proteins, and other biomolecules to study structure and function.
• Catalyst & Ligand Preparation: Acts as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	Triphenylmethyl Fluoride
CAS No.	427-36-1
Molecular Formula	C19H15F
Molecular Weight	262.32 g/mol
Synonyms	Trityl Fluoride; Fluorotriphenylmethane; Triphenylfluoromethane; (Fluoromethylene)tribenzene; α-Fluoro-α-phenyltoluene; NSC 406908; Trityl Fluoride (Triphenylmethyl Fluoride)
EINECS	207-045-6

Quality Control

Our Triphenylmethyl Fluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	96 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.