Description

2,2-Dichloro-3,3,3-Trifluoropropionic Acid is a versatile fluorinated organic acid building block, valued for its unique combination of halogen substituents. This compound is critical for introducing the trifluoromethyl and dichloromethyl motifs into complex molecules, significantly altering their physicochemical properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and chlorinated moieties to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies, contributing to desired dielectric and optical properties.
• Polymer Modification: Employed to introduce functional groups into polymer chains, creating specialty polymers with enhanced chemical resistance, surface properties, or reactivity.
• Organic Synthesis Reagent: Acts as a versatile reagent in nucleophilic substitution and condensation reactions for constructing complex organic frameworks in R&D settings.

Basic Information

Product Name	2,2-Dichloro-3,3,3-Trifluoropropionic Acid
CAS No.	422-39-9
Molecular Formula	C3HCl2F3O2
Molecular Weight	196.94 g/mol
Synonyms	2,2-Dichloro-3,3,3-trifluoropropanoic Acid; 3,3,3-Trifluoro-2,2-dichloropropionic Acid; α,α-Dichloro-β,β,β-trifluoropropionic Acid; DCTFPA; 422-39-9; NSC 88073; Propionic acid, 2,2-dichloro-3,3,3-trifluoro-
EINECS	207-015-4

Quality Control

Our 2,2-Dichloro-3,3,3-Trifluoropropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is a strong acid/organic solvent and should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.