Description

2-Amino-3,3,3-trifluoro-2-methylpropanoic acid is a specialized fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and amino functionalities make it a valuable precursor for creating molecules with enhanced metabolic stability, lipophilicity, and bioavailability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group can improve activity and environmental persistence.
• Peptidomimetics & Bioisosteres: Incorporation into peptide analogs to enhance stability against enzymatic degradation and modulate physicochemical properties.
• Material Science Research: Serves as a monomer or functional modifier in the synthesis of specialty polymers and advanced materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and labeled compounds for studying biological mechanisms.
• Catalyst & Ligand Development: Acts as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Amino-3,3,3-trifluoro-2-methylpropanoic Acid
CAS No.	422-23-1
Molecular Formula	C5H8F3NO2
Molecular Weight	171.12 g/mol
Synonyms	2-Amino-3,3,3-trifluoro-2-methylpropionic Acid; 3,3,3-Trifluoro-2-aminoisobutyric Acid; 2-Amino-2-(trifluoromethyl)propanoic Acid; 2-Methyl-2-amino-3,3,3-trifluoropropanoic Acid; 2-Amino-3,3,3-trifluoro-2-methylpropanoate; TFM-Alanine derivative; α-(Trifluoromethyl)alanine; (RS)-2-Amino-3,3,3-trifluoro-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3,3,3-trifluoro-2-methylpropanoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.