Description

2-Bromo-2,3,3,3-Tetrafluoropropionamide is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique combination of bromine and fluorine atoms, which makes it a versatile precursor for introducing fluorinated moieties into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides where fluorine substitution is desired for efficacy.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced materials with specific surface properties.
• Fluorination Chemistry: Acts as a reagent for introducing the -CF2Br or -CF3 groups into organic molecules via nucleophilic substitution or cross-coupling reactions.
• Ligand and Catalyst Development: Utilized in the preparation of fluorinated ligands for catalysis and molecular recognition studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorinated architectures.

Basic Information

Product Name	2-Bromo-2,3,3,3-Tetrafluoropropionamide
CAS No.	422-22-0
Molecular Formula	C3H2BrF4NO
Molecular Weight	223.95 g/mol
Synonyms	2-Bromo-2,3,3,3-tetrafluoropropanamide; α-Bromo-α,α,β,β-tetrafluoropropionamide; Tetrafluorobromopropionamide; Propanamide, 2-bromo-2,3,3,3-tetrafluoro-; 2,3,3,3-Tetrafluoro-2-bromopropionamide; BrC(F)(C(F)(F)F)C(=O)N
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,3,3,3-Tetrafluoropropionamide is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.