Description

Pentafluoropropionitrile is a versatile fluorinated nitrile building block, valued for its unique combination of high fluorine content and a reactive cyano group. This compound is essential for introducing the pentafluoropropionyl moiety into target molecules, significantly altering their physical and chemical properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from synthetic intermediates to specialty solvents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated groups to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Fluorinated Material Production: Acts as a monomer or modifier in the creation of specialty polymers, coatings, and liquid crystals with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Building Block: Employed in nucleophilic addition and cyclization reactions to construct complex fluorinated heterocycles and fine chemicals.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve high-voltage stability and safety performance.
• Laboratory Reagent: Utilized in research and development for method development and as a standard in analytical chemistry.

Basic Information

Product Name	Pentafluoropropionitrile
CAS No.	422-04-8
Molecular Formula	C3F5N
Molecular Weight	145.03 g/mol
Synonyms	Perfluoropropionitrile; Pentafluoropropanenitrile; 2,2,3,3,3-Pentafluoropropionitrile; PFPN; FC-216; CF3CF2CN; Perfluoropropiononitrile; Pentafluoropropionic acid nitrile
EINECS	207-000-5

Quality Control

Our Pentafluoropropionitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for extended stability. The container should be kept upright and sealed under an inert atmosphere to prevent moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density at 20°C	1.50 - 1.55 g/mL
Boiling Point	~ 45°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.