Description

2,2,3,3,3-Pentafluoropropylamine is a versatile fluorinated amine building block, distinguished by its unique pentafluoroethyl group attached to a propylamine backbone. This compound matters for its ability to impart significant lipophilicity, metabolic stability, and altered electronic properties to target molecules, making it a valuable intermediate in advanced synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas, to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric materials, leveraging its stability and specific polarity.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing properties like chemical resistance, surface energy, and thermal stability.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the 2,2,3,3,3-pentafluoropropyl group via alkylation or amination reactions in complex molecule construction.
• Surface Active Agents: Utilized in the development of specialty fluorosurfactants and coatings that require low surface tension and high stability.

Basic Information

Product Name	2,2,3,3,3-Pentafluoropropylamine
CAS No.	422-03-7
Molecular Formula	C3H4F5N
Molecular Weight	149.06 g/mol
Synonyms	1-Amino-2,2,3,3,3-pentafluoropropane; 2,2,3,3,3-Pentafluoro-1-propanamine; 3,3,3-Trifluoro-2-(trifluoromethyl)propylamine; Pentafluoropropylamine; 3-Aminopentafluoropropane; 422-03-7; 2,2,3,3,3-Pentafluoropropan-1-amine
EINECS	Contact for details

Quality Control

Our 2,2,3,3,3-Pentafluoropropylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.