Description

Trifluoromethanesulfonamide is a high-value organofluorine building block and reagent, recognized for its strong electron-withdrawing properties and stability. This compound is essential for introducing the versatile triflyl group into target molecules, enabling advanced synthesis in demanding chemical environments. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for applications ranging from catalyst development to the creation of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sulfonamide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Catalyst & Ligand Preparation: Serves as a precursor for creating highly active metal catalysts and specialized ligands in organic synthesis.
• Polymer & Material Science: Incorporated into high-performance polymers, electrolytes for batteries, and specialty surfactants.
• Fluorination Reagent: Acts as a source of the trifluoromethanesulfonyl (triflyl) group in nucleophilic and electrophilic fluorination reactions.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new reaction pathways and compound libraries.

Basic Information

Product Name	Trifluoromethanesulfonamide
CAS No.	421-85-2
Molecular Formula	CF3SO2NH2
Molecular Weight	149.09 g/mol
Synonyms	Trifluoromethanesulfonic acid amide; Triflic amide; TFSA; N-(Trifluoromethylsulfonyl)amine; 1,1,1-Trifluoro-N-sulfonylmethanamine; Trifluoromethylsulfonamide; Perfluoromethanesulfonamide; Amide of trifluoromethanesulfonic acid
EINECS	207-016-5

Quality Control

Our Trifluoromethanesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC and NMR data, to support your quality assurance and regulatory compliance needs. The product meets stringent specifications suitable for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality and stability. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	118 - 122 °C
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.