Description

2,2,2-Trifluoroethanethioamide is a specialized organofluorine building block featuring a reactive thioamide group. This compound is valued for its role as a key intermediate in the synthesis of heterocyclic compounds and fluorinated pharmaceuticals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated heterocycles, such as thiazoles and thiadiazoles, which are core structures in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for synthesizing fluorinated probes and inhibitors for studying enzymatic processes.

Basic Information

Product Name	2,2,2-Trifluoroethanethioamide
CAS No.	421-52-3
Molecular Formula	C3H2F3NS
Molecular Weight	129.11 g/mol
Synonyms	2,2,2-Trifluoroethanethioamide; Trifluoroethanethioamide; 2,2,2-Trifluoro-1-thioxoethan-1-amine; 2,2,2-Trifluoroacetothioamide; α,α,α-Trifluoroacetothioamide; TFET; TFATA
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroethanethioamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.