Description

Chlorodifluoroacetonitrile is a versatile fluorinated building block with significant synthetic utility. This compound is valued for its ability to introduce the difluoromethyl and cyano functional groups into target molecules, enabling the development of novel materials and active ingredients. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Building block for specialty polymers, liquid crystals, and electronic chemicals that require fluorinated components.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and cycloaddition reactions to construct complex heterocyclic compounds.
• Fluorine Chemistry Research: Essential reagent for academic and industrial R&D focused on developing new fluorination methodologies.

Basic Information

Product Name	Chlorodifluoroacetonitrile
CAS No.	421-05-6
Molecular Formula	C2ClF2N
Molecular Weight	111.49 g/mol
Synonyms	Difluorochloroacetonitrile; Chlorodifluoroethanenitrile; 2-Chloro-2,2-difluoroacetonitrile; Monochlorodifluoroacetonitrile; Chlorodifluoromethyl cyanide; NSC 92440; α,α-Difluoro-α-chloroacetonitrile
EINECS	Contact for details

Quality Control

Our Chlorodifluoroacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for extended stability. The container should be kept upright and securely sealed to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.