Description

2-Bromo-2,2-Difluoroethan-1-Ol is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the bromine and fluorine atoms, enabling precise molecular modifications. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for introducing difluoroethanol motifs into drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms can improve efficacy and environmental profile.
• Material Science: Serves as a precursor for fluorinated polymers, coatings, and liquid crystals with specialized properties like chemical resistance and low surface energy.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to construct complex, fluorinated organic molecules for various R&D applications.
• Ligand and Catalyst Development: Useful for synthesizing novel fluorinated ligands for metal complexes used in catalysis.

Basic Information

Product Name	2-Bromo-2,2-Difluoroethan-1-Ol
CAS No.	420-94-0
Molecular Formula	C2H3BrF2O
Molecular Weight	160.95 g/mol
Synonyms	2-Bromo-2,2-difluoroethanol; 2,2-Difluoro-2-bromoethanol; Bromodifluoroethanol; 1-Bromo-2,2-difluoroethanol; α-Bromo-α,α-difluoroethanol; NSC 84176; Ethanol, 2-bromo-2,2-difluoro-
EINECS	207-026-7

Quality Control

Our 2-Bromo-2,2-Difluoroethan-1-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.