Description

Fluoromethanol CAS NO 420-03-1 is a specialized fluorinated alcohol building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a fluorine atom and a hydroxyl group, makes it a valuable precursor for introducing fluoromethyl motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced stability, bioavailability, or specific activity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated active pharmaceutical ingredients (APIs), where the fluorine atom can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of novel fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance lipophilicity and biological activity.
• Advanced Material Precursor: Acts as a building block for synthesizing fluorinated polymers, liquid crystals, or specialty surfactants with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in laboratory-scale reactions to introduce the -CH2F group into complex organic molecules via etherification or further functionalization.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the reactivity and applications of fluorinated small molecules.

Basic Information

Product Name	Fluoromethanol
CAS No.	420-03-1
Molecular Formula	CH3FO
Molecular Weight	50.04 g/mol
Synonyms	Fluoromethanol; Fluoromethyl alcohol; Monofluoromethanol; Hydroxymethyl fluoride; Methanol, fluoro-; FLUOROMETHANOL (9CI); UNII-0B2I8E4Q4I; 420-03-1
EINECS	206-989-9

Quality Control

Our Fluoromethanol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including Gas Chromatography (GC) and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP-compliant manufacturing for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, preferably at 2-8°C. Keep away from heat, sparks, and open flame. Containers should be kept tightly sealed when not in use to prevent evaporation and potential moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (GC Area %)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.