Description

8-Fluoro-1-Octyne is a valuable fluorinated alkyne building block, distinguished by its terminal alkyne and fluorine functionalities. This compound is essential for advanced organic synthesis, enabling the introduction of both a reactive alkyne handle and a fluorine atom into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications such as click chemistry, cross-coupling reactions, and the development of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for creating fluorinated analogs via Sonogashira coupling or Huisgen cycloaddition (click chemistry).
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Materials Science: Employed in the creation of specialized polymers, liquid crystals, and advanced materials where the alkyne group allows for polymerization or functionalization.
• Chemical Biology & Bioconjugation: Acts as a probe or linker in bioconjugation strategies, leveraging the alkyne group for selective reactions with azides.
• Organic Synthesis Building Block: A versatile reagent for constructing complex molecular architectures through various carbon-carbon bond-forming reactions.

Basic Information

Product Name	8-Fluoro-1-Octyne
CAS No.	408-15-1
Molecular Formula	C8H13F
Molecular Weight	128.19 g/mol
Synonyms	1-Octyne, 8-fluoro-; 8-Fluoro-1-octyne; 8-Fluorooct-1-yne; 1-Octyne,8-fluoro-; 8-Fluoro-oct-1-yne; Fluoroalkyne C8; F-Octyne
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1-Octyne is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications such as assay and impurity profiles. Our quality systems are designed to meet the rigorous demands of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at recommended temperatures between 2°C and 8°C. Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.