Description

1-Fluoro-6-Nitrohexane is a valuable bifunctional organic building block containing both a reactive fluorine atom and a nitro group. This unique combination of functional groups makes it a versatile intermediate for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in fine chemical synthesis. The compound is offered in high purity to ensure reliable and reproducible reaction outcomes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorine incorporation for enhanced metabolic stability or bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides where the nitro and fluoro groups contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific surface properties.
• Liquid Crystal & Electronic Chemicals: Intermediate in the production of fluorinated compounds for electronic applications and display technologies.
• Organic Synthesis & Methodology Development: A valuable substrate for developing new fluorination reactions, nitro group transformations, and cascade reactions in academic and industrial laboratories.
• Cross-Coupling Reactions: The nitro group can act as a precursor for amines or be involved in metal-catalyzed coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	1-Fluoro-6-Nitrohexane
CAS No.	408-08-2
Molecular Formula	C₆H₁₂FNO₂
Molecular Weight	149.16 g/mol
Synonyms	6-Fluoro-1-nitrohexane; Hexane, 1-fluoro-6-nitro-; 1-Nitro-6-fluorohexane; 6-Fluoronitrohexane; 6-Nitro-1-fluorohexane; F(CH2)6NO2; ω-Fluoro-ω-nitrohexane; 6-Fluorohexyl nitrate (common misnomer)
EINECS	Contact for details

Quality Control

Our 1-Fluoro-6-Nitrohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (g/mL, 20°C)	1.10 - 1.20

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.