Description

16-Fluorohexadecanoic Acid Ethyl Ester is a high-purity fluorinated fatty acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom into long-chain aliphatic structures, which can dramatically alter the physical, chemical, and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel bioactive compounds, surfactants, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators, leveraging fluorine's metabolic stability and lipophilicity.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity, environmental persistence, and membrane permeability.
• Materials Science: Building block for creating fluorinated surfactants, lubricants, and surface modifiers that impart oil- and water-repellent (omniphobic) characteristics.
• Biochemical Probe Development: Acts as a precursor for synthesizing fluorinated fatty acid analogs used in metabolic pathway tracing (e.g., PET tracer development) and membrane biophysics studies.
• Organic Synthesis: Versatile starting material for further functionalization via the ester group, enabling chain extension, reduction to alcohols, or hydrolysis to the corresponding acid.

Basic Information

Product Name	16-Fluorohexadecanoic Acid Ethyl Ester
CAS No.	408-07-1
Molecular Formula	C₁₈H₃₅FO₂
Molecular Weight	302.47 g/mol
Synonyms	Ethyl 16-Fluorohexadecanoate; Ethyl 16-Fluoropalmitate; 16-Fluoro-palmitic Acid Ethyl Ester; Hexadecanoic Acid, 16-Fluoro-, Ethyl Ester; ω-Fluorohexadecanoic Acid Ethyl Ester; 16-Fluorohexadecanoic Acid Ethyl Ester; Ethyl ω-Fluoropalmitate; 16-Fluoropalmitic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 16-Fluorohexadecanoic Acid Ethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including GC, HPLC, NMR, and MS, for comprehensive identity confirmation and impurity profiling. Certificates of Analysis (COA) detailing purity, assay, and specific tests are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR / NMR)	Conforms to structure
Assay (GC / HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.