Description

Acetamide, 2,2,2-Trifluoro-n-(2,2,2-Trifluoroethyl)- is a specialized fluorinated acetamide derivative, a high-value intermediate prized for its unique chemical reactivity and fluorine content. This compound is critical for introducing trifluoroethylamino groups into target molecules, enabling the synthesis of advanced materials and pharmaceuticals with enhanced properties. It is primarily sought by research institutions and industrial manufacturers in the agrochemical, pharmaceutical, and advanced materials sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs where the trifluoroethyl group can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination often leads to increased efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce fluorine-containing side chains into polymers, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial organic chemistry laboratories for constructing complex molecules via nucleophilic substitution or condensation reactions.
• Fluorinated Surfactant & Coating Intermediate: Used in the development of specialty surfactants and high-performance coatings that require oil and water repellency (e.g., stain-resistant fabrics).

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2,2,2-Trifluoroethyl)-
CAS No.	407-37-4
Molecular Formula	C6H5F6NO
Molecular Weight	209.10 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2,2,2-trifluoroethyl)acetamide; 1,1,1-Trifluoro-2-[(2,2,2-trifluoroacetyl)amino]ethane; TFEA; Trifluoroacetamide, N-(2,2,2-trifluoroethyl)-; Acetamide, N-(2,2,2-trifluoroethyl)-2,2,2-trifluoro-; 407-37-4; EINECS 206-983-9
EINECS	206-983-9

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2,2,2-Trifluoroethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.