Description

Bistrifluoroacetamide is a specialized fluorinated organic compound with the CAS registry number 407-24-9. This high-purity reagent is valued for its role as a versatile trifluoroacetylating agent and a key building block in advanced synthetic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise fluorination and derivatization capabilities.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the trifluoroacetyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine moiety enhances biological activity and environmental persistence.
• Analytical Chemistry: Employed as a derivatization agent in gas chromatography (GC) and mass spectrometry (MS) for the analysis of amines, alcohols, and other functional groups to improve volatility and detection.
• Material Science: Serves as a precursor for fluorinated polymers, coatings, and liquid crystals, imparting valuable properties such as chemical resistance, thermal stability, and low surface energy.
• Peptide & Protein Research: Utilized in biochemistry for the selective protection and modification of amino groups during peptide synthesis.
• Organic Synthesis: A fundamental building block for constructing complex molecules in academic and industrial R&D laboratories, enabling novel carbon-fluorine bond formations.

Basic Information

Product Name	Bistrifluoroacetamide
CAS No.	407-24-9
Molecular Formula	C4H2F6N2O2
Molecular Weight	224.06 g/mol
Synonyms	N,N-Bis(trifluoroacetyl)amine; Bis(trifluoroacetyl)amine; Di(trifluoroacetyl)amine; 2,2,2-Trifluoro-N-(2,2,2-trifluoroacetyl)acetamide; BTFAA; Bistrifluoroacetic acid amide; Trifluoroacetamide, N-(trifluoroacetyl)-; 1,1,1-Trifluoro-N-(2,2,2-trifluoroacetyl)methanamine
EINECS	206-983-8

Quality Control

Our Bistrifluoroacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.