Description

1-Bromo-4-(Trifluoromethoxy)Benzene is a high-value halogenated aromatic building block characterized by its bromine and trifluoromethoxy substituents. This compound matters for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both bromo and fluorinated alkoxy functionalities into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Functional Material Research: Employed in academic and industrial R&D for developing novel polymers, ligands, and specialty chemicals with tailored properties.

Basic Information

Product Name	1-Bromo-4-(Trifluoromethoxy)Benzene
CAS No.	407-14-7
Molecular Formula	C7H4BrF3O
Molecular Weight	241.01 g/mol
Synonyms	4-Bromo-α,α,α-trifluoroanisole; p-Bromophenyl trifluoromethyl ether; 4-Bromophenyl trifluoromethyl ether; 1-Bromo-4-(trifluoromethoxy)benzene; 4-Bromo-1-(trifluoromethoxy)benzene; Benzene, 1-bromo-4-(trifluoromethoxy)-; (4-Bromophenyl)(trifluoromethyl) ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature: 2-25°C. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.